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Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension
Dural arteriovenous fistulas (dAVF) refer to an aberrant connection between an artery and a vein within the dura. Although the pathogenesis of dAVF is unclear, a link to cerebral venous thrombosis (CVT) has been posited though not fully identified. The current case is the first report demonstrating...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275228/ https://www.ncbi.nlm.nih.gov/pubmed/30555948 http://dx.doi.org/10.1016/j.ensci.2018.11.015 |
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author | Kang, Min Kyoung Cho, Young-Dae Kang, Hyun-Seung Jung, Keun-Hwa |
author_facet | Kang, Min Kyoung Cho, Young-Dae Kang, Hyun-Seung Jung, Keun-Hwa |
author_sort | Kang, Min Kyoung |
collection | PubMed |
description | Dural arteriovenous fistulas (dAVF) refer to an aberrant connection between an artery and a vein within the dura. Although the pathogenesis of dAVF is unclear, a link to cerebral venous thrombosis (CVT) has been posited though not fully identified. The current case is the first report demonstrating dAVF formation following CVT according to dynamic changes in the intracranial pressure and venous drainage pattern. This observation provides insight into the pathophysiological association between dAVF and CVT. A 60-year-old woman presented with acute onset of a severe headache and first-onset seizure. Initial magnetic resonance imaging showed an extensive thrombosis in the cerebral venous sinuses. However, there was no evidence of any vascular malformation. Eight months later, she reported dizziness, visual obscurations and pulsatile tinnitus. Follow-up digital subtraction angiography showed multiple dAVFs. Endovascular treatments for the dAVF embolization was performed twice, resulting in the obliteration of the dAVF along with the resolution of her optic disc edema, visual obscurations and tinnitus. The degree and pattern of the venous pressure, not hypoxia-induced growth factors, are the key pathogenic mechanisms of dAVF following CVT. Oral anticoagulants and good adherence do not ensure the prevention of dAVF. Thus, careful clinical observation and follow-up examinations are recommended. |
format | Online Article Text |
id | pubmed-6275228 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-62752282018-12-14 Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension Kang, Min Kyoung Cho, Young-Dae Kang, Hyun-Seung Jung, Keun-Hwa eNeurologicalSci Case Report Dural arteriovenous fistulas (dAVF) refer to an aberrant connection between an artery and a vein within the dura. Although the pathogenesis of dAVF is unclear, a link to cerebral venous thrombosis (CVT) has been posited though not fully identified. The current case is the first report demonstrating dAVF formation following CVT according to dynamic changes in the intracranial pressure and venous drainage pattern. This observation provides insight into the pathophysiological association between dAVF and CVT. A 60-year-old woman presented with acute onset of a severe headache and first-onset seizure. Initial magnetic resonance imaging showed an extensive thrombosis in the cerebral venous sinuses. However, there was no evidence of any vascular malformation. Eight months later, she reported dizziness, visual obscurations and pulsatile tinnitus. Follow-up digital subtraction angiography showed multiple dAVFs. Endovascular treatments for the dAVF embolization was performed twice, resulting in the obliteration of the dAVF along with the resolution of her optic disc edema, visual obscurations and tinnitus. The degree and pattern of the venous pressure, not hypoxia-induced growth factors, are the key pathogenic mechanisms of dAVF following CVT. Oral anticoagulants and good adherence do not ensure the prevention of dAVF. Thus, careful clinical observation and follow-up examinations are recommended. Elsevier 2018-11-22 /pmc/articles/PMC6275228/ /pubmed/30555948 http://dx.doi.org/10.1016/j.ensci.2018.11.015 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Kang, Min Kyoung Cho, Young-Dae Kang, Hyun-Seung Jung, Keun-Hwa Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension |
title | Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension |
title_full | Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension |
title_fullStr | Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension |
title_full_unstemmed | Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension |
title_short | Development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension |
title_sort | development of a dural arteriovenous fistula subsequent to cerebral venous thrombosis by venous hypertension |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275228/ https://www.ncbi.nlm.nih.gov/pubmed/30555948 http://dx.doi.org/10.1016/j.ensci.2018.11.015 |
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