Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective

Bacterial chromosomes have a single, unique replication origin (named oriC), from which DNA synthesis starts. This study describes methods of visualizing oriC regions and the chromosome replication in single living bacterial cells in real-time. This review also discusses the impact of live cell imag...

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Autores principales: Trojanowski, Damian, Hołówka, Joanna, Zakrzewska-Czerwińska, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275241/
https://www.ncbi.nlm.nih.gov/pubmed/30534115
http://dx.doi.org/10.3389/fmicb.2018.02819
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author Trojanowski, Damian
Hołówka, Joanna
Zakrzewska-Czerwińska, Jolanta
author_facet Trojanowski, Damian
Hołówka, Joanna
Zakrzewska-Czerwińska, Jolanta
author_sort Trojanowski, Damian
collection PubMed
description Bacterial chromosomes have a single, unique replication origin (named oriC), from which DNA synthesis starts. This study describes methods of visualizing oriC regions and the chromosome replication in single living bacterial cells in real-time. This review also discusses the impact of live cell imaging techniques on understanding of chromosome replication dynamics, particularly at the initiation step, in different species of bacteria.
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spelling pubmed-62752412018-12-10 Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective Trojanowski, Damian Hołówka, Joanna Zakrzewska-Czerwińska, Jolanta Front Microbiol Microbiology Bacterial chromosomes have a single, unique replication origin (named oriC), from which DNA synthesis starts. This study describes methods of visualizing oriC regions and the chromosome replication in single living bacterial cells in real-time. This review also discusses the impact of live cell imaging techniques on understanding of chromosome replication dynamics, particularly at the initiation step, in different species of bacteria. Frontiers Media S.A. 2018-11-26 /pmc/articles/PMC6275241/ /pubmed/30534115 http://dx.doi.org/10.3389/fmicb.2018.02819 Text en Copyright © 2018 Trojanowski, Hołówka and Zakrzewska-Czerwińska. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Trojanowski, Damian
Hołówka, Joanna
Zakrzewska-Czerwińska, Jolanta
Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective
title Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective
title_full Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective
title_fullStr Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective
title_full_unstemmed Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective
title_short Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective
title_sort where and when bacterial chromosome replication starts: a single cell perspective
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275241/
https://www.ncbi.nlm.nih.gov/pubmed/30534115
http://dx.doi.org/10.3389/fmicb.2018.02819
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