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Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis
Lipocalin-2 is a constituent of the neutrophil secondary granules and is expressed de novo by macrophages and epithelium in response to inflammation. Lipocalin-2 acts in a bacteriostatic fashion by binding iron-loaded siderophores required for bacterial growth. Mycobacterium tuberculosis (M.tb) prod...
Autores principales: | Dahl, Sara Louise, Woodworth, Joshua S., Lerche, Christian Johann, Cramer, Elisabeth Præstekjær, Nielsen, Pia Rude, Moser, Claus, Thomsen, Allan Randrup, Borregaard, Niels, Cowland, Jack Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275245/ https://www.ncbi.nlm.nih.gov/pubmed/30534124 http://dx.doi.org/10.3389/fimmu.2018.02717 |
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