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Inhibitors of BMP‐1/tolloid‐like proteinases: efficacy, selectivity and cellular toxicity

BMP‐1/tolloid‐like proteinases belong to the astacin family of human metalloproteinases, together with meprins and ovastacin. They represent promising targets to treat or prevent a wide range of diseases such as fibrotic disorders or cancer. However, the study of their pathophysiological roles is st...

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Detalles Bibliográficos
Autores principales: Talantikite, Maya, Lécorché, Pascaline, Beau, Fabrice, Damour, Odile, Becker‐Pauly, Christoph, Ho, Wen‐Bin, Dive, Vincent, Vadon‐Le Goff, Sandrine, Moali, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275283/
https://www.ncbi.nlm.nih.gov/pubmed/30524951
http://dx.doi.org/10.1002/2211-5463.12540