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Critical role of tristetraprolin and AU‐rich element RNA‐binding protein 1 in the suppression of cancer cell growth by globular adiponectin

Adiponectin exhibits potent antitumor activities. Herein, we examined the molecular mechanisms underlying suppression of tumor growth by globular adiponectin (gAcrp). We demonstrated that gAcrp suppressed B‐cell lymphoma 2 (Bcl‐2) expression, an anti‐apoptotic gene, by inducing its mRNA destabilizat...

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Detalles Bibliográficos
Autores principales: Tilija Pun, Nirmala, Khakurel, Amrita, Shrestha, Aastha, Kim, Sang‐Hyun, Park, Pil‐Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275284/
https://www.ncbi.nlm.nih.gov/pubmed/30524947
http://dx.doi.org/10.1002/2211-5463.12541