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Iron in the Tumor Microenvironment—Connecting the Dots
Iron metabolism and tumor biology are intimately linked. Iron facilitates the production of oxygen radicals, which may either result in iron-induced cell death, ferroptosis, or contribute to mutagenicity and malignant transformation. Once transformed, malignant cells require high amounts of iron for...
Autores principales: | Pfeifhofer-Obermair, Christa, Tymoszuk, Piotr, Petzer, Verena, Weiss, Günter, Nairz, Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275298/ https://www.ncbi.nlm.nih.gov/pubmed/30534534 http://dx.doi.org/10.3389/fonc.2018.00549 |
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