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Treatment of fibrillary glomerulonephritis with use of repository corticotropin injections

Fibrillary glomerulonephritis (FGN) is a rare idiopathic condition linked to malignancy, autoimmune disorders, monoclonal gammopathies and hepatitis C virus. It usually has a poor prognosis, resulting in progression to end-stage renal disease within a few years, given the lack of standardized treatm...

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Detalles Bibliográficos
Autores principales: Maroz, Natallia, Reuben, Sharon, Nadasdy, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275454/
https://www.ncbi.nlm.nih.gov/pubmed/30524713
http://dx.doi.org/10.1093/ckj/sfy009
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author Maroz, Natallia
Reuben, Sharon
Nadasdy, Tibor
author_facet Maroz, Natallia
Reuben, Sharon
Nadasdy, Tibor
author_sort Maroz, Natallia
collection PubMed
description Fibrillary glomerulonephritis (FGN) is a rare idiopathic condition linked to malignancy, autoimmune disorders, monoclonal gammopathies and hepatitis C virus. It usually has a poor prognosis, resulting in progression to end-stage renal disease within a few years, given the lack of standardized treatment. Repository corticotrophin (RC) injections are approved for use in a variety of nephrotic syndromes, but are not routinely considered for treatment of FGN. We present a case in which a patient with FGN began treatment with RC 3 months after diagnosis. The patient has attained partial remission with complete resolution of nephrotic syndrome and stabilization of renal function.
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spelling pubmed-62754542018-12-06 Treatment of fibrillary glomerulonephritis with use of repository corticotropin injections Maroz, Natallia Reuben, Sharon Nadasdy, Tibor Clin Kidney J Rare Diseases Fibrillary glomerulonephritis (FGN) is a rare idiopathic condition linked to malignancy, autoimmune disorders, monoclonal gammopathies and hepatitis C virus. It usually has a poor prognosis, resulting in progression to end-stage renal disease within a few years, given the lack of standardized treatment. Repository corticotrophin (RC) injections are approved for use in a variety of nephrotic syndromes, but are not routinely considered for treatment of FGN. We present a case in which a patient with FGN began treatment with RC 3 months after diagnosis. The patient has attained partial remission with complete resolution of nephrotic syndrome and stabilization of renal function. Oxford University Press 2018-12 2018-03-20 /pmc/articles/PMC6275454/ /pubmed/30524713 http://dx.doi.org/10.1093/ckj/sfy009 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of ERA-EDTA. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Rare Diseases
Maroz, Natallia
Reuben, Sharon
Nadasdy, Tibor
Treatment of fibrillary glomerulonephritis with use of repository corticotropin injections
title Treatment of fibrillary glomerulonephritis with use of repository corticotropin injections
title_full Treatment of fibrillary glomerulonephritis with use of repository corticotropin injections
title_fullStr Treatment of fibrillary glomerulonephritis with use of repository corticotropin injections
title_full_unstemmed Treatment of fibrillary glomerulonephritis with use of repository corticotropin injections
title_short Treatment of fibrillary glomerulonephritis with use of repository corticotropin injections
title_sort treatment of fibrillary glomerulonephritis with use of repository corticotropin injections
topic Rare Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275454/
https://www.ncbi.nlm.nih.gov/pubmed/30524713
http://dx.doi.org/10.1093/ckj/sfy009
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