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Folding pathway of an Ig domain is conserved on and off the ribosome

Proteins that fold cotranslationally may do so in a restricted configurational space, due to the volume occupied by the ribosome. How does this environment, coupled with the close proximity of the ribosome, affect the folding pathway of a protein? Previous studies have shown that the cotranslational...

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Detalles Bibliográficos
Autores principales:	Tian, Pengfei, Steward, Annette, Kudva, Renuka, Su, Ting, Shilling, Patrick J., Nickson, Adrian A., Hollins, Jeffrey J., Beckmann, Roland, von Heijne, Gunnar, Clarke, Jane, Best, Robert B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275497/ https://www.ncbi.nlm.nih.gov/pubmed/30413621 http://dx.doi.org/10.1073/pnas.1810523115

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