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Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics

Biomechanical cues dynamically control major cellular processes, but whether genetic variants actively participate in mechanosensing mechanisms remains unexplored. Vascular homeostasis is tightly regulated by hemodynamics. Exposure to disturbed blood flow at arterial sites of branching and bifurcati...

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Detalles Bibliográficos
Autores principales:	Krause, Matthew D., Huang, Ru-Ting, Wu, David, Shentu, Tzu-Pin, Harrison, Devin L., Whalen, Michael B., Stolze, Lindsey K., Di Rienzo, Anna, Moskowitz, Ivan P., Civelek, Mete, Romanoski, Casey E., Fang, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275533/ https://www.ncbi.nlm.nih.gov/pubmed/30429326 http://dx.doi.org/10.1073/pnas.1810568115

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