Orphan nuclear hormone receptor NR4A1 interacts with HPV16 E2 regulatory protein

The human NR4A1 orphan receptor is a member of the TR3 steroid receptor superfamily, which binds DNA at the NBRE and NurRE responsive elements. The TR3 receptors are involved in the regulation of differentiation, proliferation and apoptosis. We report that NR4A1 interacts with human papillomavirus t...

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Autores principales: Olejnik-Schmidt, Agnieszka K., Schmidt, Marcin T., Goździcka-Józefiak, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2006
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275592/
https://www.ncbi.nlm.nih.gov/pubmed/16847753
http://dx.doi.org/10.2478/s11658-006-0010-x
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author Olejnik-Schmidt, Agnieszka K.
Schmidt, Marcin T.
Goździcka-Józefiak, Anna
author_facet Olejnik-Schmidt, Agnieszka K.
Schmidt, Marcin T.
Goździcka-Józefiak, Anna
author_sort Olejnik-Schmidt, Agnieszka K.
collection PubMed
description The human NR4A1 orphan receptor is a member of the TR3 steroid receptor superfamily, which binds DNA at the NBRE and NurRE responsive elements. The TR3 receptors are involved in the regulation of differentiation, proliferation and apoptosis. We report that NR4A1 interacts with human papillomavirus type 16 (HPV16) E2 protein — a key papillomavirus regulatory factor. This interaction might be involved in the transcription regulation of the HPV16 genes and the regulation of infected cell homeostasis.
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spelling pubmed-62755922018-12-10 Orphan nuclear hormone receptor NR4A1 interacts with HPV16 E2 regulatory protein Olejnik-Schmidt, Agnieszka K. Schmidt, Marcin T. Goździcka-Józefiak, Anna Cell Mol Biol Lett Short Communication The human NR4A1 orphan receptor is a member of the TR3 steroid receptor superfamily, which binds DNA at the NBRE and NurRE responsive elements. The TR3 receptors are involved in the regulation of differentiation, proliferation and apoptosis. We report that NR4A1 interacts with human papillomavirus type 16 (HPV16) E2 protein — a key papillomavirus regulatory factor. This interaction might be involved in the transcription regulation of the HPV16 genes and the regulation of infected cell homeostasis. Versita 2006-03-01 /pmc/articles/PMC6275592/ /pubmed/16847753 http://dx.doi.org/10.2478/s11658-006-0010-x Text en © University of Wrocław 2006
spellingShingle Short Communication
Olejnik-Schmidt, Agnieszka K.
Schmidt, Marcin T.
Goździcka-Józefiak, Anna
Orphan nuclear hormone receptor NR4A1 interacts with HPV16 E2 regulatory protein
title Orphan nuclear hormone receptor NR4A1 interacts with HPV16 E2 regulatory protein
title_full Orphan nuclear hormone receptor NR4A1 interacts with HPV16 E2 regulatory protein
title_fullStr Orphan nuclear hormone receptor NR4A1 interacts with HPV16 E2 regulatory protein
title_full_unstemmed Orphan nuclear hormone receptor NR4A1 interacts with HPV16 E2 regulatory protein
title_short Orphan nuclear hormone receptor NR4A1 interacts with HPV16 E2 regulatory protein
title_sort orphan nuclear hormone receptor nr4a1 interacts with hpv16 e2 regulatory protein
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275592/
https://www.ncbi.nlm.nih.gov/pubmed/16847753
http://dx.doi.org/10.2478/s11658-006-0010-x
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