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The in vitro effects of 2-methoxyestradiol-bis-sulphamate on cell numbers, membrane integrity and cell morphology, and the possible induction of apoptosis and autophagy in a non-tumorigenic breast epithelial cell line
2-methoxyestradiol (2ME2) exerts estrogen receptor-independent anti-proliferative, anti-angiogenic and anti-tumor activity in vitro and in vivo. Due to its low bioavailability and rapid metabolic degradation, several analogues have been developed in recent years. 2-methoxyestradiol-bis-sulphamate (2...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SP Versita
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275594/ https://www.ncbi.nlm.nih.gov/pubmed/20697831 http://dx.doi.org/10.2478/s11658-010-0030-4 |