Cargando…

Novel estradiol analogue induces apoptosis and autophagy in esophageal carcinoma cells

Cancer is the second leading cause of death in South Africa. The critical role that microtubules play in cell division makes them an ideal target for the development of chemotherapeutic drugs that prevent the hyperproliferation of cancer cells. The new in silico-designed estradiol analogue 2-ethyl-3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wolmarans, Elize, Mqoco, Thandi V., Stander, Andre, Nkandeu, Sandra D., Sippel, Katherine, McKenna, Robert, Joubert, Annie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Versita 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275608/ https://www.ncbi.nlm.nih.gov/pubmed/24563014 http://dx.doi.org/10.2478/s11658-014-0183-7

Ejemplares similares

Induction of the intrinsic apoptotic pathway via a new antimitotic agent in an esophageal carcinoma cell line
por: Wolmarans, Elize, et al.
Publicado: (2014)

Sulphamoylated estradiol analogue induces antiproliferative activity and apoptosis in breast cell lines
por: Visagie, Michelle, et al.
Publicado: (2012)

In Vitro Evaluation of ESE-15-ol, an Estradiol Analogue with Nanomolar Antimitotic and Carbonic Anhydrase Inhibitory Activity
por: Stander, Barend Andre, et al.
Publicado: (2012)

Ultrastructural changes of erythrocytes in whole blood after exposure to prospective in silico-designed anticancer agents: a qualitative case study
por: Repsold, Lisa, et al.
Publicado: (2014)

Signaling Pathways of ESE-16, an Antimitotic and Anticarbonic Anhydrase Estradiol Analog, in Breast Cancer Cells
por: Stander, Barend Andre, et al.
Publicado: (2013)

Correction: Signaling Pathways of ESE-16, an Antimitotic and Anticarbonic Anhydrase Estradiol Analog, in Breast Cancer Cells
por: Stander, Barend Andre, et al.
Publicado: (2013)

Sulphamoylated 2-Methoxyestradiol Analogues Induce Apoptosis in Adenocarcinoma Cell Lines
por: Visagie, Michelle, et al.
Publicado: (2013)

A Combination of an Antimitotic and a Bromodomain 4 Inhibitor Synergistically Inhibits the Metastatic MDA-MB-231 Breast Cancer Cell Line
por: Mqoco, Thandi, et al.
Publicado: (2019)

Ex vivo apoptotic and autophagic influence of an estradiol analogue on platelets
por: Repsold, Lisa, et al.
Publicado: (2016)

Molecular crosstalk between apoptosis and autophagy induced by a novel 2-methoxyestradiol analogue in cervical adenocarcinoma cells
por: Theron, Anne E, et al.
Publicado: (2013)

Single-Cell Transcriptome Analysis of Human Adipose-Derived Stromal Cells Identifies a Contractile Cell Subpopulation
por: Wolmarans, Elize, et al.
Publicado: (2021)

Influence of partial and complete glutamine-and glucose deprivation of breast-and cervical tumorigenic cell lines
por: Visagie, Michelle Helen, et al.
Publicado: (2015)

Sulphamoylated Estradiol Analogue Induces Reactive Oxygen Species Generation to Exert Its Antiproliferative Activity in Breast Cancer Cell Lines
por: Lebelo, Maphuti T., et al.
Publicado: (2020)

Dysregulation of Catalase by a Sulphamoylated Estradiol Analogue Culminates in Antimitotic Activity and Cell Death Induction in Breast Cancer Cell Lines
por: Lebelo, Maphuti T., et al.
Publicado: (2021)

An overview of the role of platelets in angiogenesis, apoptosis and autophagy in chronic myeloid leukaemia
por: Repsold, Lisa, et al.
Publicado: (2017)

Characterization of Signalling Pathways That Link Apoptosis and Autophagy to Cell Death Induced by Estrone Analogues Which Reversibly Depolymerize Microtubules
por: Mercier, Anne E., et al.
Publicado: (2021)

Side Population: Its Use in the Study of Cellular Heterogeneity and as a Potential Enrichment Tool for Rare Cell Populations
por: Wolmarans, Elize, et al.
Publicado: (2018)

Flow cytometric analysis of platelets type 2 diabetes mellitus reveals ‘angry’ platelets
por: Soma, Prashilla, et al.
Publicado: (2016)

Interaction of Estradiol and Endoplasmic Reticulum Stress in the Development of Esophageal Carcinoma
por: Wang, Chen, et al.
Publicado: (2020)

A bis-sulphamoylated estradiol derivative induces ROS-dependent cell cycle abnormalities and subsequent apoptosis
por: Visagie, Michelle Helen, et al.
Publicado: (2017)

Up-regulation of SIRT1 induced by 17beta-estradiol promotes autophagy and inhibits apoptosis in osteoblasts
por: Wang, Yu, et al.
Publicado: (2021)

Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo
por: O’Donovan, Tracey R., et al.
Publicado: (2015)

Autophagy induced by a sulphamoylated estrone analogue contributes to its cytotoxic effect on breast cancer cells
por: Verwey, Marcel, et al.
Publicado: (2016)

UBE2L6/UBCH8 and ISG15 attenuate autophagy in esophageal cancer cells
por: Falvey, Chloe M., et al.
Publicado: (2017)

Estradiol-independent restoration of T-cell function in post-reproductive females
por: King, Tristin L., et al.
Publicado: (2023)

The in vitro effects of 2-methoxyestradiol-bis-sulphamate on cell numbers, membrane integrity and cell morphology, and the possible induction of apoptosis and autophagy in a non-tumorigenic breast epithelial cell line
por: Visagie, Michelle H., et al.
Publicado: (2010)

PIWIL2 interacting with IKK to regulate autophagy and apoptosis in esophageal squamous cell carcinoma
por: Zhao, Xu, et al.
Publicado: (2021)

Correction: UBE2L6/UBCH8 and ISG15 attenuate autophagy in esophageal cancer cells
por: Falvey, Chloe M., et al.
Publicado: (2020)

Apoptosis and autophagy markers predict survival in neoadjuvant treated oesophageal adenocarcinoma patients
por: El Mashed, Shereen, et al.
Publicado: (2022)

Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling
por: Feng, Y, et al.
Publicado: (2014)

MiR-126 promotes esophageal squamous cell carcinoma via inhibition of apoptosis and autophagy
por: Li, Mingli, et al.
Publicado: (2020)

Transgender Girls Grow Tall: Adult Height Is Unaffected by GnRH Analogue and Estradiol Treatment
por: Boogers, Lidewij Sophia, et al.
Publicado: (2022)

The in vitro effects of a novel estradiol analog on cell proliferation and morphology in human epithelial cervical carcinoma
por: Boyd, Laura Susan, et al.
Publicado: (2018)

Estradiol and progesterone regulate proliferation and apoptosis in colon cancer
por: Sasso, Corina Verónica, et al.
Publicado: (2019)

Estradiol signaling mediates gender difference in visceral adiposity via autophagy
por: Tao, Zhipeng, et al.
Publicado: (2018)

Dysfunction of apoptosis and autophagy correlates with local recurrence in esophageal squamous cell carcinoma after definitive chemoradiation
por: Qiu, Hu, et al.
Publicado: (2021)

An estrogen analogue and promising anticancer agent refrains from inducing morphological damage and reactive oxygen species generation in erythrocytes, fibrin and platelets: a pilot study
por: Repsold, Lisa, et al.
Publicado: (2014)

Herpes simplex virus esophagitis in an immunocompetent teenaged girl
por: McKenna, Dennis P., et al.
Publicado: (2006)

17β-estradiol ameliorates oxidative stress and blue light-emitting diode-induced retinal degeneration by decreasing apoptosis and enhancing autophagy
por: Wei, Qingquan, et al.
Publicado: (2018)

Feasibility of Imaging Esophageal Cancer with Labeled Somatostatin Analogue
por: Herlin, Gunnar, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_smp5i3v7iud5g30da3qbv7kcfc