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SHP-2 and PTP-pest induction during Rb-E2F associated apoptosis

Apoptosis is intimately connected to cell cycle regulation via the Retinoblastoma (Rb)-E2F pathway and thereby serves an essential role in tumor suppression by eliminating aberrant hyperproliferative cells. Upon loss of Rb activity, an apoptotic response can be elicited through both p53-dependent an...

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Detalles Bibliográficos
Autores principales:	Morales, Liza D., Pena, Karina, Kim, Dae Joon, Lieman, Jonathan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SP Versita 2012
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275625/ https://www.ncbi.nlm.nih.gov/pubmed/22644489 http://dx.doi.org/10.2478/s11658-012-0020-9

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