Cargando…

ZFAT is a critical molecule for cell survival in mouse embryonic fibroblasts

ZFAT was originally identified as an immune-related transcriptional regulator containing 18 C2H2-type zinc-finger domains and one AT-hook. ZFAT is highly conserved among species and functions as an anti-apoptotic molecule in the lymphoblastic leukemia cell line, MOLT-4. We recently demonstrated that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Doi, Keiko, Fujimoto, Takahiro, Koyanagi, Midori, Tsunoda, Toshiyuki, Tanaka, Yoko, Yoshida, Yasuhiro, Takashima, Yasuo, Kuroki, Masahide, Sasazuki, Takehiko, Shirasawa, Senji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SP Versita 2010
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275631/ https://www.ncbi.nlm.nih.gov/pubmed/21225468 http://dx.doi.org/10.2478/s11658-010-0041-1

Ejemplares similares

ZFAT is essential for endothelial cell assembly and the branch point formation of capillary-like structures in an angiogenesis model
por: Yoshida, Yasuhiro, et al.
Publicado: (2010)

Zfat expression in ZsGreen reporter gene knock-in mice: Implications for a novel function of Zfat in definitive erythropoiesis
por: Tsunoda, Toshiyuki, et al.
Publicado: (2018)

The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes
por: Ishikura, Shuhei, et al.
Publicado: (2021)

Zfat-Deficiency Results in a Loss of CD3ζ Phosphorylation with Dysregulation of ERK and Egr Activities Leading to Impaired Positive Selection
por: Ogawa, Masahiro, et al.
Publicado: (2013)

CENP-B promotes the centromeric localization of ZFAT to control transcription of noncoding RNA
por: Ishikura, Shuhei, et al.
Publicado: (2021)

Death domain–associated protein DAXX regulates noncoding RNA transcription at the centromere through the transcription regulator ZFAT
por: Ishikura, Shuhei, et al.
Publicado: (2022)

Altered Energy Homeostasis and Resistance to Diet-Induced Obesity in KRAP-Deficient Mice
por: Fujimoto, Takahiro, et al.
Publicado: (2009)

Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
por: Tochio, Naoya, et al.
Publicado: (2015)

ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B–H4K8ac–BRD4 axis
por: Ishikura, Shuhei, et al.
Publicado: (2020)

Inhibition of Phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model
por: Tsunoda, Toshiyuki, et al.
Publicado: (2012)

Tespa1 is a novel inositol 1,4,5-trisphosphate receptor binding protein in T and B lymphocytes
por: Matsuzaki, Hiroshi, et al.
Publicado: (2012)

ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line
por: Nishi, Kensuke, et al.
Publicado: (2017)

Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP(3)R in the stomach and kidney
por: FUJIMOTO, TAKAHIRO, et al.
Publicado: (2012)

BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study
por: Makrodouli, Eleni, et al.
Publicado: (2011)

Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase()()
por: Toda, Kosuke, et al.
Publicado: (2016)

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells
por: Goulielmaki, Maria, et al.
Publicado: (2016)

Genetic polymorphisms involved in dopaminergic neurotransmission and risk for Parkinson's disease in a Japanese population
por: Kiyohara, Chikako, et al.
Publicado: (2011)

Effects of Aspergillus fumigatus Conidia on Apoptosis and Proliferation in an In Vitro Model of the Lung Microenvironment
por: Kushima, Hisako, et al.
Publicado: (2021)

ZFAT gene variant association with multiple sclerosis in the Arabian Gulf population: A genetic basis for gender-associated susceptibility
por: Bourguiba-Hachemi, Sonia, et al.
Publicado: (2016)

Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1
por: Kandasamy, Palanivel, et al.
Publicado: (2021)

p120RasGAP Is a Mediator of Rho Pathway Activation and Tumorigenicity in the DLD1 Colorectal Cancer Cell Line
por: Organ, Shawna L., et al.
Publicado: (2014)

Embryonic Hematopoietic Progenitor Cells Reside in Muscle before Bone Marrow Hematopoiesis
por: Tanaka, Yuka, et al.
Publicado: (2015)

Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells
por: Yuen, Hiu-Fung, et al.
Publicado: (2012)

Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS-activated pancreatic cancer cells
por: Terado, Tokio, et al.
Publicado: (2022)

Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90
por: Ernst, Anne, et al.
Publicado: (2020)

Epipharyngeal Abrasive Therapy (EAT) Has Potential as a Novel Method for Long COVID Treatment
por: Imai, Kazuaki, et al.
Publicado: (2022)

In Hyperthermia Increased ERK and WNT Signaling Suppress Colorectal Cancer Cell Growth
por: Bordonaro, Michael, et al.
Publicado: (2016)

Targeted disruption of the K-Ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis
por: Allgayer, H, et al.
Publicado: (1999)

Epipharyngeal Abrasive Therapy (EAT) Reduces the mRNA Expression of Major Proinflammatory Cytokine IL-6 in Chronic Epipharyngitis
por: Nishi, Kensuke, et al.
Publicado: (2022)

Myosin synthesis in embryonic chicken fibroblasts
Publicado: (1979)

Fibroblast-Induced Paradoxical PI3K Pathway Activation in PTEN-Competent Colorectal Cancer: Implications for Therapeutic PI3K/mTOR Inhibition
por: Conciatori, Fabiana, et al.
Publicado: (2022)

Highly Restricted T Cell Repertoire Shaped by a Single Major Histocompatibility Complex–Peptide Ligand in the Presence of a Single Rearranged T Cell Receptor β Chain
por: Fukui, Yoshinori, et al.
Publicado: (1998)

Cryptochrome Genes Are Highly Expressed in the Ovary of the African Clawed Frog, Xenopus tropicalis
por: Kubo, Yoko, et al.
Publicado: (2010)

Epigenetic analysis of bovine parthenogenetic embryonic fibroblasts
por: KANEDA, Masahiro, et al.
Publicado: (2017)

Newcastle disease virus infection in chicken embryonic fibroblasts but not duck embryonic fibroblasts is associated with elevated host innate immune response
por: Kang, Yinfeng, et al.
Publicado: (2016)

Induction of primordial germ cell-like cells from common marmoset embryonic stem cells by inhibition of WNT and retinoic acid signaling
por: Shono, Mayumi, et al.
Publicado: (2023)

ACTION ON FIBROBLASTS OF THE PROTEIN FRACTION OF EMBRYONIC TISSUE EXTRACT
por: Baker, Lillian E., et al.
Publicado: (1926)

Dioxin Induces Genomic Instability in Mouse Embryonic Fibroblasts
por: Korkalainen, Merja, et al.
Publicado: (2012)

A comparison of strategies for immortalizing mouse embryonic fibroblasts
por: Amand, Melissa M. St., et al.
Publicado: (2016)

Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions
por: Saitou, Mitinori, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_vpn8rqf0q6pmdqvgsp905i67lv