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Silencing of the type 1 insulin-like growth factor receptor increases the sensitivity to apoptosis and inhibits invasion in human lung adenocarcinoma A549 cells
The type 1 insulin-like growth factor receptor (IGF-1R), which is over-expressed or activated in many human cancers, including lung cancer, mediates cancer cell proliferation and metastasis. Several studies indicate that blocking IGF-1R expression can inhibit tumor cell proliferation and metastasis....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Versita
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275632/ https://www.ncbi.nlm.nih.gov/pubmed/17588222 http://dx.doi.org/10.2478/s11658-007-0022-1 |