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Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase

The activity of indoleamine 2, 3-dioxygenase (IDO; E.C. 1.13.11.42) catalyzes the oxidative cleavage of tryptophan to form kynurenine. IDO activity consumes superoxide anions; therefore, we postulated that over-expression of IDO might mitigate superoxide-anion dependent, oxidative modification of ce...

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Detalles Bibliográficos
Autores principales:	Keskin, Derin B., Marshall, Brendan, Munn, David, Mellor, Andrew L., Gearhart, Debra A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Versita 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275707/ https://www.ncbi.nlm.nih.gov/pubmed/17103092 http://dx.doi.org/10.2478/s11658-006-0048-9

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