The antioxidant properties of carnitine in vitro

Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS(•+), and to protect fluorescein against bleaching induced by AAPH-derived peroxyl radicals and p...

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Detalles Bibliográficos
Autores principales: Solarska, Katarzyna, Lewińska, Anna, Karowicz-Bilińska, Agata, Bartosz, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275708/
https://www.ncbi.nlm.nih.gov/pubmed/19936630
http://dx.doi.org/10.2478/s11658-009-0036-y
Descripción
Sumario:Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS(•+), and to protect fluorescein against bleaching induced by AAPH-derived peroxyl radicals and peroxynitrite, thiol groups against oxidation induced by hydrogen peroxide, peroxyl radicals, hypochlorite and peroxynitrite, and erythrocytes against hemolysis induced by peroxyl radicals and hypochlorite. These results show that carnitine has a direct antioxidant action against physiologically relevant oxidants.

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