Cargando…

The antioxidant properties of carnitine in vitro

Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS(•+), and to protect fluorescein against bleaching induced by AAPH-derived peroxyl radicals and p...

Descripción completa

Detalles Bibliográficos
Autores principales: Solarska, Katarzyna, Lewińska, Anna, Karowicz-Bilińska, Agata, Bartosz, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275708/
https://www.ncbi.nlm.nih.gov/pubmed/19936630
http://dx.doi.org/10.2478/s11658-009-0036-y
_version_ 1783377860022501376
author Solarska, Katarzyna
Lewińska, Anna
Karowicz-Bilińska, Agata
Bartosz, Grzegorz
author_facet Solarska, Katarzyna
Lewińska, Anna
Karowicz-Bilińska, Agata
Bartosz, Grzegorz
author_sort Solarska, Katarzyna
collection PubMed
description Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS(•+), and to protect fluorescein against bleaching induced by AAPH-derived peroxyl radicals and peroxynitrite, thiol groups against oxidation induced by hydrogen peroxide, peroxyl radicals, hypochlorite and peroxynitrite, and erythrocytes against hemolysis induced by peroxyl radicals and hypochlorite. These results show that carnitine has a direct antioxidant action against physiologically relevant oxidants.
format Online
Article
Text
id pubmed-6275708
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher SP Versita
record_format MEDLINE/PubMed
spelling pubmed-62757082018-12-10 The antioxidant properties of carnitine in vitro Solarska, Katarzyna Lewińska, Anna Karowicz-Bilińska, Agata Bartosz, Grzegorz Cell Mol Biol Lett Short Communication Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS(•+), and to protect fluorescein against bleaching induced by AAPH-derived peroxyl radicals and peroxynitrite, thiol groups against oxidation induced by hydrogen peroxide, peroxyl radicals, hypochlorite and peroxynitrite, and erythrocytes against hemolysis induced by peroxyl radicals and hypochlorite. These results show that carnitine has a direct antioxidant action against physiologically relevant oxidants. SP Versita 2009-11-20 /pmc/articles/PMC6275708/ /pubmed/19936630 http://dx.doi.org/10.2478/s11658-009-0036-y Text en © © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009
spellingShingle Short Communication
Solarska, Katarzyna
Lewińska, Anna
Karowicz-Bilińska, Agata
Bartosz, Grzegorz
The antioxidant properties of carnitine in vitro
title The antioxidant properties of carnitine in vitro
title_full The antioxidant properties of carnitine in vitro
title_fullStr The antioxidant properties of carnitine in vitro
title_full_unstemmed The antioxidant properties of carnitine in vitro
title_short The antioxidant properties of carnitine in vitro
title_sort antioxidant properties of carnitine in vitro
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275708/
https://www.ncbi.nlm.nih.gov/pubmed/19936630
http://dx.doi.org/10.2478/s11658-009-0036-y
work_keys_str_mv AT solarskakatarzyna theantioxidantpropertiesofcarnitineinvitro
AT lewinskaanna theantioxidantpropertiesofcarnitineinvitro
AT karowiczbilinskaagata theantioxidantpropertiesofcarnitineinvitro
AT bartoszgrzegorz theantioxidantpropertiesofcarnitineinvitro
AT solarskakatarzyna antioxidantpropertiesofcarnitineinvitro
AT lewinskaanna antioxidantpropertiesofcarnitineinvitro
AT karowiczbilinskaagata antioxidantpropertiesofcarnitineinvitro
AT bartoszgrzegorz antioxidantpropertiesofcarnitineinvitro