High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone

In this paper, we describe the isolation and characterization of two PC3 subclones. One subclone, mr, showed an epithelial phenotype, the other, M1, showed a sarcomatous morphology. Transplanted into nude mice, mr developed tumors at a dramatically faster rate than M1. Comparing the two subclones, d...

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Detalles Bibliográficos
Autores principales: Hirokawa, Yoshifumi S., Takagi, Akimitsu, Uchida, Katsunori, Kozuka, Yuji, Yoneda, Misao, Watanabe, Masatoshi, Shiraishi, Taizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275712/
https://www.ncbi.nlm.nih.gov/pubmed/17318295
http://dx.doi.org/10.2478/s11658-007-0009-y
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author Hirokawa, Yoshifumi S.
Takagi, Akimitsu
Uchida, Katsunori
Kozuka, Yuji
Yoneda, Misao
Watanabe, Masatoshi
Shiraishi, Taizo
author_facet Hirokawa, Yoshifumi S.
Takagi, Akimitsu
Uchida, Katsunori
Kozuka, Yuji
Yoneda, Misao
Watanabe, Masatoshi
Shiraishi, Taizo
author_sort Hirokawa, Yoshifumi S.
collection PubMed
description In this paper, we describe the isolation and characterization of two PC3 subclones. One subclone, mr, showed an epithelial phenotype, the other, M1, showed a sarcomatous morphology. Transplanted into nude mice, mr developed tumors at a dramatically faster rate than M1. Comparing the two subclones, differentially expressed genes were identified, including E-cadherin, IL-8 and STAG1/PMEPA1. These genes were expressed at higher levels in mr than in M1.
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spelling pubmed-62757122018-12-10 High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone Hirokawa, Yoshifumi S. Takagi, Akimitsu Uchida, Katsunori Kozuka, Yuji Yoneda, Misao Watanabe, Masatoshi Shiraishi, Taizo Cell Mol Biol Lett Article In this paper, we describe the isolation and characterization of two PC3 subclones. One subclone, mr, showed an epithelial phenotype, the other, M1, showed a sarcomatous morphology. Transplanted into nude mice, mr developed tumors at a dramatically faster rate than M1. Comparing the two subclones, differentially expressed genes were identified, including E-cadherin, IL-8 and STAG1/PMEPA1. These genes were expressed at higher levels in mr than in M1. Versita 2007-02-23 /pmc/articles/PMC6275712/ /pubmed/17318295 http://dx.doi.org/10.2478/s11658-007-0009-y Text en © University of Wrocław 2007
spellingShingle Article
Hirokawa, Yoshifumi S.
Takagi, Akimitsu
Uchida, Katsunori
Kozuka, Yuji
Yoneda, Misao
Watanabe, Masatoshi
Shiraishi, Taizo
High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
title High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
title_full High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
title_fullStr High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
title_full_unstemmed High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
title_short High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
title_sort high level expression of stag1/pmepa1 in an androgen-independent prostate cancer pc3 subclone
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275712/
https://www.ncbi.nlm.nih.gov/pubmed/17318295
http://dx.doi.org/10.2478/s11658-007-0009-y
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