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Rapid proliferation of activated lymph node CD4(+) T cells is achieved by greatly curtailing the duration of gap phases in cell cycle progression

Peripheral T cells are in G0 phase and do not proliferate. When they encounter an antigen, they enter the cell cycle and proliferate in order to initiate an active immune response. Here, we have determined the first two cell cycle times of a leading population of CD4(+) T cells stimulated by PMA plu...

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Detalles Bibliográficos
Autores principales: Mishima, Takuya, Toda, Shoko, Ando, Yoshiaki, Matsunaga, Tsukasa, Inobe, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275717/
https://www.ncbi.nlm.nih.gov/pubmed/25424911
http://dx.doi.org/10.2478/s11658-014-0219-z

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