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Molecularly targeting the PI3K-Akt-mTOR pathway can sensitize cancer cells to radiotherapy and chemotherapy

Radiotherapy and chemotherapeutic agents that damage DNA are the current major non-surgical means of treating cancer. However, many patients develop resistances to chemotherapy drugs in their later lives. The PI3K and Ras signaling pathways are deregulated in most cancers, so molecularly targeting P...

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Detalles Bibliográficos
Autores principales: Wang, Ziwen, Huang, Yujung, Zhang, Jiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275747/
https://www.ncbi.nlm.nih.gov/pubmed/24728800
http://dx.doi.org/10.2478/s11658-014-0191-7