STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL

Cutaneous T-cell lymphomas (CTCLs) are non-Hodgkin’s lymphomas resulting from clonal expansion and localization of malignant T-lymphocytes to the skin. CTCL cells have defective apoptosis. Signal transducers and activators of transcription (STAT) are a family of transcription factors known to play i...

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Detalles Bibliográficos
Autores principales: Verma, Navin K., Davies, Anthony M., Long, Aideen, Kelleher, Dermot, Volkov, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275771/
https://www.ncbi.nlm.nih.gov/pubmed/20213502
http://dx.doi.org/10.2478/s11658-010-0008-2

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