Cargando…
The role of advanced glycation end products in various types of neurodegenerative disease: a therapeutic approach
Protein glycation is initiated by a nucleophilic addition reaction between the free amino group from a protein, lipid or nucleic acid and the carbonyl group of a reducing sugar. This reaction forms a reversible Schiff base, which rearranges over a period of days to produce ketoamine or Amadori produ...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Versita
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275793/ https://www.ncbi.nlm.nih.gov/pubmed/25141979 http://dx.doi.org/10.2478/s11658-014-0205-5 |