Cargando…

LRH1 as a promising prognostic biomarker and predictor of metastasis in patients with non‐small cell lung cancer

BACKGROUND: LRH1, which promotes the malignant transformation of carcinoma, has recently been documented in several types of malignancies. However, LRH1 has not been assessed as a potential clinical biomarker in any cancer. METHODS: LRH1 expression was tested in fresh‐frozen tissue samples with quan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yuechao, Xing, Ying, Wang, Hongmei, Yan, Shi, Wang, Xinzhu, Cai, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275822/ https://www.ncbi.nlm.nih.gov/pubmed/30273983 http://dx.doi.org/10.1111/1759-7714.12887

Ejemplares similares

PHLPP2 as a novel metastatic and prognostic biomarker in non‐small cell lung cancer patients
por: Wang, Hongmei, et al.
Publicado: (2019)

LRH1 Acts as an Oncogenic Driver in Human Osteosarcoma and Pan-Cancer
por: Song, Yang, et al.
Publicado: (2021)

[Retracted] MicroRNA‑381 serves as a prognostic factor and inhibits migration and invasion in non‑small cell lung cancer by targeting LRH‑1
por: Tian, Chunyan, et al.
Publicado: (2023)

Identification of transcription factors and single nucleotide polymorphisms of Lrh1 and its homologous genes in Lrh1-knockout pancreas of mice
por: Tang, Maochun, et al.
Publicado: (2014)

Human FXR Regulates SHP Expression through Direct Binding to an LRH-1 Binding Site, Independent of an IR-1 and LRH-1
por: Hoeke, Martijn O., et al.
Publicado: (2014)

Overexpression of Romo1 is an unfavorable prognostic biomarker and a predictor of lymphatic metastasis in non-small cell lung cancer patients
por: Kim, Hong Jun, et al.
Publicado: (2018)

Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators
por: Cato, Michael L., et al.
Publicado: (2023)

Targeting LRH-1 in hepatoblastoma cell lines causes decreased proliferation
por: Jin, Jingling, et al.
Publicado: (2019)

CPSF3 is a promising prognostic biomarker and predicts recurrence of non-small cell lung cancer
por: Ning, Yue, et al.
Publicado: (2019)

WDR5 is a prognostic biomarker of brain metastasis from non-small cell lung cancer
por: Li, Zheng, et al.
Publicado: (2022)

LINC02678 as a Novel Prognostic Marker Promotes Aggressive Non-small-cell Lung Cancer
por: Jia, Dexin, et al.
Publicado: (2021)

LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer
por: Xu, Pan, et al.
Publicado: (2016)

Antidiabetic actions of a phosphatidylcholine ligand for nuclear receptor LRH-1
por: Lee, Jae Man, et al.
Publicado: (2011)

Nuclear Receptor LRH-1 Induces the Reproductive Neuropeptide Kisspeptin in the Hypothalamus
por: Atkin, Stan D., et al.
Publicado: (2013)

Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist
por: Mays, Suzanne G., et al.
Publicado: (2020)

Telomere Status of Advanced Non-Small-Cell Lung Cancer Offers a Novel Promising Prognostic and Predictive Biomarker
por: Faugeras, Eve, et al.
Publicado: (2022)

LRH1 Promotes Tumor Cell Proliferation and Migration and Is Correlated With Poor Prognosis in Ovarian Cancer
por: Sun, Wenzhou, et al.
Publicado: (2020)

LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival
por: Bayrer, James R., et al.
Publicado: (2018)

LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness
por: Pang, Jia-Min B., et al.
Publicado: (2017)

Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
por: Birgersson, Madeleine, et al.
Publicado: (2023)

Circular RNAs Are Promising Biomarkers in Liquid Biopsy for the Diagnosis of Non-small Cell Lung Cancer
por: Huang, Lanxiang, et al.
Publicado: (2021)

Metastasis-associated in colon cancer-1 and aldehyde dehydrogenase 1 are metastatic and prognostic biomarker for non-small cell lung cancer
por: Zhou, Lei, et al.
Publicado: (2016)

Combinations of plasma cfDNA concentration, integrity and tumor markers are promising biomarkers for early diagnosis of non-small cell lung cancer
por: Ren, Sai, et al.
Publicado: (2023)

The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
por: Mueller, Matthias, et al.
Publicado: (2006)

Another One Bites the Gut: Nuclear Receptor LRH-1 in Intestinal Regeneration and Cancer
por: Zerlotin, Roberta, et al.
Publicado: (2021)

LRH-1 induces hepatoprotective nonessential amino acids in response to acute liver injury
por: Klatt, Kevin C., et al.
Publicado: (2023)

MDM2 binding protein as a predictor of metastasis and a novel prognostic biomarker in patients with gastric cancer
por: Wang, Wei, et al.
Publicado: (2017)

Prognostic Ability of Enhancer RNAs in Metastasis of Non-Small Cell Lung Cancer
por: Liu, Jun, et al.
Publicado: (2022)

TRPM4 and TRPV2 are two novel prognostic biomarkers and promising targeted therapy in UVM
por: Wang, Jiong, et al.
Publicado: (2022)

Predictive and Prognostic Biomarkers for Lung Cancer Bone Metastasis and Their Therapeutic Value
por: Chai, Xupeng, et al.
Publicado: (2021)

TNFAIP8 promotes the proliferation and cisplatin chemoresistance of non-small cell lung cancer through MDM2/p53 pathway
por: Xing, Ying, et al.
Publicado: (2018)

ARL14 as a Prognostic Biomarker in Non-Small Cell Lung Cancer
por: Zhang, Binbin, et al.
Publicado: (2021)

KIAA1522 is a novel prognostic biomarker in patients with non-small cell lung cancer
por: Liu, Yi-Zhen, et al.
Publicado: (2016)

Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation
por: Chanda, Dipanjan, et al.
Publicado: (2010)

LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus
por: Cobo-Vuilleumier, Nadia, et al.
Publicado: (2018)

LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis
por: Joo, Min Sung, et al.
Publicado: (2019)

Targeting LRH-1/NR5A2 to treat type 1 diabetes mellitus
por: Cobo-Vuilleumier, Nadia, et al.
Publicado: (2018)

Regulation of the Intestinal Extra-Adrenal Steroidogenic Pathway Component LRH-1 by Glucocorticoids in Ulcerative Colitis
por: Landskron, Glauben, et al.
Publicado: (2022)

LRH‐1/NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance
por: Michalek, Svenja, et al.
Publicado: (2022)

The nuclear receptor LRH‐1 discriminates between ligands using distinct allosteric signaling circuits
por: Mays, Suzanne G., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sdk7r9net344fq3hlb4q85jckr