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Increased pressure stimulates aberrant dendritic cell maturation

Patients with malignancy typically exhibit abnormal dendritic cell profiles. Interstitial tumor pressure is increased 20-50mmHg over that in normal tissue. We hypothesized that elevated pressure in the tumor microenvironment may influence dendritic cell (DC) phenotype and function. Monocyte-derived...

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Detalles Bibliográficos
Autores principales: Craig, David H., Schaubert, Keri L., Shiratsuchi, Hiroe, Kan-Mitchell, June, Basson, Marc D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Versita 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275900/
https://www.ncbi.nlm.nih.gov/pubmed/18161009
http://dx.doi.org/10.2478/s11658-007-0054-6