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Increased pressure stimulates aberrant dendritic cell maturation
Patients with malignancy typically exhibit abnormal dendritic cell profiles. Interstitial tumor pressure is increased 20-50mmHg over that in normal tissue. We hypothesized that elevated pressure in the tumor microenvironment may influence dendritic cell (DC) phenotype and function. Monocyte-derived...
Autores principales: | Craig, David H., Schaubert, Keri L., Shiratsuchi, Hiroe, Kan-Mitchell, June, Basson, Marc D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Versita
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275900/ https://www.ncbi.nlm.nih.gov/pubmed/18161009 http://dx.doi.org/10.2478/s11658-007-0054-6 |
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