Cargando…
The effect of TGF-β1 and Smad7 gene transfer on the phenotypic changes of rat alveolar epithelial cells
The aim of this study was to investigate whether transforming growth factor-β1 (TGF-β1) could induce alveolar epithelial-mesenchymal transition (EMT) in vitro, and whether Smad7 gene transfer could block this transition. We also aimed to elucidate the possible mechanisms of these processes. The Smad...
Autores principales: | Xu, Guo-Ping, Li, Qing-Quan, Cao, Xi-Xi, Chen, Qi, Zhao, Zhong-Hua, Diao, Zi-Qiang, Xu, Zu-De |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Versita
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275908/ https://www.ncbi.nlm.nih.gov/pubmed/17457524 http://dx.doi.org/10.2478/s11658-007-0018-x |
Ejemplares similares
-
Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via Smad-Dependent and Smad-Independent Signaling Pathways
por: Zhou, Xian-Long, et al.
Publicado: (2017) -
Pan-Phosphodiesterase Inhibitors Attenuate TGF-β-Induced Pro-Fibrotic Phenotype in Alveolar Epithelial Type II Cells by Downregulating Smad-2 Phosphorylation
por: Wójcik-Pszczoła, Katarzyna, et al.
Publicado: (2022) -
CDCA7 promotes TGF‐β‐induced epithelial–mesenchymal transition via transcriptionally regulating Smad4/Smad7 in ESCC
por: Li, Hongyi, et al.
Publicado: (2022) -
COX-2/sEH Dual Inhibitor PTUPB Attenuates Epithelial-Mesenchymal Transformation of Alveolar Epithelial Cells via Nrf2-Mediated Inhibition of TGF-β1/Smad Signaling
por: Zhang, Chen-Yu, et al.
Publicado: (2022) -
Effects of tacrolimus on the TGF-β1/SMAD signaling pathway in paraquat-exposed rat alveolar type II epithelial cells
por: Ren, Yingli, et al.
Publicado: (2020)