The NTPase/helicase domain of hepatitis C virus nonstructural protein 3 inhibits protein kinase C independently of its NTPase activity

Helicase motif VI is a short arginine-rich motif within the NTPase/helicase domain of the non-structural protein 3 (NS3) of the hepatitis C virus (HCV). We previously demonstrated that it reduces the catalytic activity and intracellular shuttling of protein kinase C (PKC). Thus, NS3-mediated PKC inh...

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Detalles Bibliográficos
Autores principales: Hartjen, Philip, Höchst, Bastian, Heim, Denise, von der Kammer, Henning, Lucke, Judith, Reinholz, Michael, Baier, Andrea, Smeets, Ralf, Wege, Henning, Borowski, Peter, Wiesch, Julian Schulze Zur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275940/
https://www.ncbi.nlm.nih.gov/pubmed/23893289
http://dx.doi.org/10.2478/s11658-013-0099-7

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