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Stability of the N-Terminal Helix and Its Role in Amyloid Formation of Serum Amyloid A
[Image: see text] Colonic amyloidosis is the result of overexpression of the serum amyloid A (SAA) protein in inflammatory bowel disease or colon cancer. Crucial for amyloid formation are the first ten N-terminal residues, which in the crystal structure are a part of a 27-residue long helix. Here, w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275945/ https://www.ncbi.nlm.nih.gov/pubmed/30533585 http://dx.doi.org/10.1021/acsomega.8b02377 |