Photoinduced Ligand Release from a Silicon Phthalocyanine Dye Conjugated with Monoclonal Antibodies: A Mechanism of Cancer Cell Cytotoxicity after Near-Infrared Photoimmunotherapy

[Image: see text] Photochemical reactions can dramatically alter physical characteristics of reacted molecules. In this study, we demonstrate that near-infrared (NIR) light induces an axial ligand-releasing reaction, which dramatically alters hydrophilicity of a silicon phthalocyanine derivative (IR...

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Detalles Bibliográficos
Autores principales: Sato, Kazuhide, Ando, Kanta, Okuyama, Shuhei, Moriguchi, Shiho, Ogura, Tairo, Totoki, Shinichiro, Hanaoka, Hirofumi, Nagaya, Tadanobu, Kokawa, Ryohei, Takakura, Hideo, Nishimura, Masayuki, Hasegawa, Yoshinori, Choyke, Peter L., Ogawa, Mikako, Kobayashi, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276043/
https://www.ncbi.nlm.nih.gov/pubmed/30555909
http://dx.doi.org/10.1021/acscentsci.8b00565

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