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Sulphamoylated estradiol analogue induces antiproliferative activity and apoptosis in breast cell lines
Research into potential anticancer agents has shown that 2-methoxyestradiol exerts antiproliferative activity in vitro and in vivo in an estrogen receptor-independent manner. Due to its limited biological accessibility and rapid metabolic degradation, several new analogues have been developed in rec...
Autores principales: | Visagie, Michelle, Mqoco, Thandi, Joubert, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Versita
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276056/ https://www.ncbi.nlm.nih.gov/pubmed/22933044 http://dx.doi.org/10.2478/s11658-012-0030-7 |
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