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Diversity analysis of MSP1 identifies conserved epitope organization in block 2 amidst high sequence variability in Indian Plasmodium falciparum isolates

BACKGROUND: Despite its immunogenicity, the polymorphic nature of merozoite surface protein 1, an important vaccine candidate for Plasmodium falciparum malaria, remains a concern. This study analyses the impact of genetic variability and parasite population structure on epitope organization of diffe...

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Detalles Bibliográficos
Autores principales: Ghoshal, Sharmistha, Gajendra, Pragya, Datta Kanjilal, Sumana, Mitra, Mitashree, Sengupta, Sanghamitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276175/
https://www.ncbi.nlm.nih.gov/pubmed/30509263
http://dx.doi.org/10.1186/s12936-018-2592-y