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Diversity analysis of MSP1 identifies conserved epitope organization in block 2 amidst high sequence variability in Indian Plasmodium falciparum isolates
BACKGROUND: Despite its immunogenicity, the polymorphic nature of merozoite surface protein 1, an important vaccine candidate for Plasmodium falciparum malaria, remains a concern. This study analyses the impact of genetic variability and parasite population structure on epitope organization of diffe...
Autores principales: | Ghoshal, Sharmistha, Gajendra, Pragya, Datta Kanjilal, Sumana, Mitra, Mitashree, Sengupta, Sanghamitra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276175/ https://www.ncbi.nlm.nih.gov/pubmed/30509263 http://dx.doi.org/10.1186/s12936-018-2592-y |
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