GM604 regulates developmental neurogenesis pathways and the expression of genes associated with amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is currently an incurable disease without highly effective pharmacological treatments. The peptide drug GM604 (GM6 or Alirinetide) was developed as a candidate ALS therapy, which has demonstrated safety and good drug-like properties with a favorable ph...

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Detalles Bibliográficos
Autores principales: Swindell, William R., Bojanowski, Krzysztof, Kindy, Mark S., Chau, Raymond M. W., Ko, Dorothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276193/
https://www.ncbi.nlm.nih.gov/pubmed/30524706
http://dx.doi.org/10.1186/s40035-018-0135-7

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