Integrated proteotranscriptomics of breast cancer reveals globally increased protein-mRNA concordance associated with subtypes and survival

BACKGROUND: Transcriptome analysis of breast cancer discovered distinct disease subtypes of clinical significance. However, it remains a challenge to define disease biology solely based on gene expression because tumor biology is often the result of protein function. Here, we measured global proteom...

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Detalles Bibliográficos
Autores principales: Tang, Wei, Zhou, Ming, Dorsey, Tiffany H., Prieto, DaRue A., Wang, Xin W., Ruppin, Eytan, Veenstra, Timothy D., Ambs, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276229/
https://www.ncbi.nlm.nih.gov/pubmed/30501643
http://dx.doi.org/10.1186/s13073-018-0602-x

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