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ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2(Q607R)

BACKGROUND: RNA editing by adenosine deaminases acting on RNA (ADARs) converts adenosines to inosines (A-to-I) in RNA, that alters gene expression and generates protein diversity. Dysregulation of A-to-I editing has been found associated with a number of nervous system diseases. However, the role of...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Wang, Kuanyu, Zhao, Zheng, Sun, Si, Zhang, Kenan, Huang, Ruoyu, Zeng, Fan, Hu, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276233/
https://www.ncbi.nlm.nih.gov/pubmed/30524204
http://dx.doi.org/10.1186/s12935-018-0695-8