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Impact of relative dose intensity on bone marrow suppression induced by S-1: retrospective observational study

BACKGROUND: S-1 (a combination of tegafur, gimeracil, and oteracil) is used to treat various cancers. Bone marrow suppression is a dose-limiting toxicity of S-1. The relationship between relative dose intensity (RDI) and bone marrow suppression has not been investigated. Hence, we aimed to elucidate...

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Detalles Bibliográficos
Autores principales:	Hirai, Toshinori, Ogawa, Ryuichi, Yamaga, Ryosuke, Itoh, Toshimasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276246/ https://www.ncbi.nlm.nih.gov/pubmed/30524750 http://dx.doi.org/10.1186/s40780-018-0127-x

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