A strategy to identify a ketoreductase that preferentially synthesizes pharmaceutically relevant (S)-alcohols using whole-cell biotransformation

INTRODUCTION: Chemical industries are constantly in search of an expeditious and environmentally benign method for producing chiral synthons. Ketoreductases have been used as catalysts for enantioselective conversion of desired prochiral ketones to their corresponding alcohol. We chose reported prom...

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Detalles Bibliográficos
Autores principales: Haq, Saiful F., Shanbhag, Anirudh P., Karthikeyan, Subbulakshmi, Hassan, Imran, Thanukrishnan, Kannan, Ashok, Abhishek, Sukumaran, Sunilkumar, Ramaswamy, S., Bharatham, Nagakumar, Datta, Santanu, Samant, Shalaka, Katagihallimath, Nainesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276252/
https://www.ncbi.nlm.nih.gov/pubmed/30509260
http://dx.doi.org/10.1186/s12934-018-1036-2

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