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Genetic Diversity of Bovine Viral Diarrhea Virus Infection in Goats in Southwestern China
Bovine viral diarrhea virus (BVDV) affects cows, pigs, sheep, goats, and other ruminants, as well as some wild animals. BVDV causes considerable economic losses every year and many countries have developed programs aimed at the eradication of this disease. The genetic diversity of BVDV in diseased g...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276411/ https://www.ncbi.nlm.nih.gov/pubmed/30581873 http://dx.doi.org/10.1155/2018/8274397 |
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author | Deng, Yu Wang, Silu Liu, Runxia Hao, Guiying |
author_facet | Deng, Yu Wang, Silu Liu, Runxia Hao, Guiying |
author_sort | Deng, Yu |
collection | PubMed |
description | Bovine viral diarrhea virus (BVDV) affects cows, pigs, sheep, goats, and other ruminants, as well as some wild animals. BVDV causes considerable economic losses every year and many countries have developed programs aimed at the eradication of this disease. The genetic diversity of BVDV in diseased goats has never been described in southwestern China. Thus, in this study, we applied antigen-capture ELISA and RT-PCR to survey the infection rate of BVDV in diseased goats in this region. Our results demonstrated that the average BVDV infection rate in goats was 17.51%, with all positive samples indicating infection by BVDV-1 and not BVDV-2, BVDV-3, or Border disease virus. The molecular characteristics of the 5′-untranslated region (5′-UTR) of BVDV-1 were recognized as belonging predominantly to the BVDV-1a, 1b, 1c, 1m, and 1p subtypes. BVDV-1b and 1m were the most abundant subtypes identified in this region, similar to the BVDV epidemics in cattle in other regions of China. This is the first study that describes the genetic characterization of BVDV in sick goats from southwestern China and is important for future studies and control programs. |
format | Online Article Text |
id | pubmed-6276411 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-62764112018-12-23 Genetic Diversity of Bovine Viral Diarrhea Virus Infection in Goats in Southwestern China Deng, Yu Wang, Silu Liu, Runxia Hao, Guiying J Vet Med Research Article Bovine viral diarrhea virus (BVDV) affects cows, pigs, sheep, goats, and other ruminants, as well as some wild animals. BVDV causes considerable economic losses every year and many countries have developed programs aimed at the eradication of this disease. The genetic diversity of BVDV in diseased goats has never been described in southwestern China. Thus, in this study, we applied antigen-capture ELISA and RT-PCR to survey the infection rate of BVDV in diseased goats in this region. Our results demonstrated that the average BVDV infection rate in goats was 17.51%, with all positive samples indicating infection by BVDV-1 and not BVDV-2, BVDV-3, or Border disease virus. The molecular characteristics of the 5′-untranslated region (5′-UTR) of BVDV-1 were recognized as belonging predominantly to the BVDV-1a, 1b, 1c, 1m, and 1p subtypes. BVDV-1b and 1m were the most abundant subtypes identified in this region, similar to the BVDV epidemics in cattle in other regions of China. This is the first study that describes the genetic characterization of BVDV in sick goats from southwestern China and is important for future studies and control programs. Hindawi 2018-11-18 /pmc/articles/PMC6276411/ /pubmed/30581873 http://dx.doi.org/10.1155/2018/8274397 Text en Copyright © 2018 Yu Deng et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Deng, Yu Wang, Silu Liu, Runxia Hao, Guiying Genetic Diversity of Bovine Viral Diarrhea Virus Infection in Goats in Southwestern China |
title | Genetic Diversity of Bovine Viral Diarrhea Virus Infection in Goats in Southwestern China |
title_full | Genetic Diversity of Bovine Viral Diarrhea Virus Infection in Goats in Southwestern China |
title_fullStr | Genetic Diversity of Bovine Viral Diarrhea Virus Infection in Goats in Southwestern China |
title_full_unstemmed | Genetic Diversity of Bovine Viral Diarrhea Virus Infection in Goats in Southwestern China |
title_short | Genetic Diversity of Bovine Viral Diarrhea Virus Infection in Goats in Southwestern China |
title_sort | genetic diversity of bovine viral diarrhea virus infection in goats in southwestern china |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276411/ https://www.ncbi.nlm.nih.gov/pubmed/30581873 http://dx.doi.org/10.1155/2018/8274397 |
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