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Quasispecies Changes with Distinctive Point Mutations in the Hepatitis C Virus Internal Ribosome Entry Site (IRES) Derived from PBMCs and Plasma

The 5' untranslated region (UTR) of the hepatitis C virus (HCV) genome contains the internal ribosome entry site (IRES), a highly conserved RNA structure essential for cap-independent translation of the viral polyprotein. HCV, apart from the liver, is thought to be associated with lymphocyte su...

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Detalles Bibliográficos
Autores principales: Mercuri, Luca, Thomson, Emma C., Hughes, Joseph, Karayiannis, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276526/
https://www.ncbi.nlm.nih.gov/pubmed/30581467
http://dx.doi.org/10.1155/2018/4835252

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