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Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up
The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”. The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276544/ https://www.ncbi.nlm.nih.gov/pubmed/30555861 http://dx.doi.org/10.1016/j.dib.2018.10.075 |
Sumario: | The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”. The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually transmitted disease (STD). Live Treponema pallidum (T. pallidum, Tp) and inactivated T. pallidum were inoculated in the backs of New Zealand rabbits. RT-PCR was performed to determine whether T. pallidum DNA could be detected in different groups. Sixty paired serum samples from patients at follow-up were tested by RPR and recombinant Tp0971-, Tp0768-, Tp0462- and Tp92-based ELISA. |
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