Cargando…

Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up

The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”. The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wen, Zhang, Xiaohong, Zhao, Tie, Zhou, Chenglong, Duan, Junxia, Zhao, Feijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276544/
https://www.ncbi.nlm.nih.gov/pubmed/30555861
http://dx.doi.org/10.1016/j.dib.2018.10.075
Descripción
Sumario:The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”. The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually transmitted disease (STD). Live Treponema pallidum (T. pallidum, Tp) and inactivated T. pallidum were inoculated in the backs of New Zealand rabbits. RT-PCR was performed to determine whether T. pallidum DNA could be detected in different groups. Sixty paired serum samples from patients at follow-up were tested by RPR and recombinant Tp0971-, Tp0768-, Tp0462- and Tp92-based ELISA.