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Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up
The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”. The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276544/ https://www.ncbi.nlm.nih.gov/pubmed/30555861 http://dx.doi.org/10.1016/j.dib.2018.10.075 |
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author | Liu, Wen Zhang, Xiaohong Zhao, Tie Zhou, Chenglong Duan, Junxia Zhao, Feijun |
author_facet | Liu, Wen Zhang, Xiaohong Zhao, Tie Zhou, Chenglong Duan, Junxia Zhao, Feijun |
author_sort | Liu, Wen |
collection | PubMed |
description | The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”. The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually transmitted disease (STD). Live Treponema pallidum (T. pallidum, Tp) and inactivated T. pallidum were inoculated in the backs of New Zealand rabbits. RT-PCR was performed to determine whether T. pallidum DNA could be detected in different groups. Sixty paired serum samples from patients at follow-up were tested by RPR and recombinant Tp0971-, Tp0768-, Tp0462- and Tp92-based ELISA. |
format | Online Article Text |
id | pubmed-6276544 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-62765442018-12-14 Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up Liu, Wen Zhang, Xiaohong Zhao, Tie Zhou, Chenglong Duan, Junxia Zhao, Feijun Data Brief Immunology and Microbiology The data presented in this article are related to the research article entitled “Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination”. The rabbit model [1], [2] is an appropriate animal model for studying syphilis, a classic sexually transmitted disease (STD). Live Treponema pallidum (T. pallidum, Tp) and inactivated T. pallidum were inoculated in the backs of New Zealand rabbits. RT-PCR was performed to determine whether T. pallidum DNA could be detected in different groups. Sixty paired serum samples from patients at follow-up were tested by RPR and recombinant Tp0971-, Tp0768-, Tp0462- and Tp92-based ELISA. Elsevier 2018-11-07 /pmc/articles/PMC6276544/ /pubmed/30555861 http://dx.doi.org/10.1016/j.dib.2018.10.075 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Immunology and Microbiology Liu, Wen Zhang, Xiaohong Zhao, Tie Zhou, Chenglong Duan, Junxia Zhao, Feijun Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up |
title | Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up |
title_full | Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up |
title_fullStr | Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up |
title_full_unstemmed | Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up |
title_short | Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up |
title_sort | data on the generation of rabbit infections and rpr titre changes in serum samples from syphilis patients at follow-up |
topic | Immunology and Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276544/ https://www.ncbi.nlm.nih.gov/pubmed/30555861 http://dx.doi.org/10.1016/j.dib.2018.10.075 |
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