MED12 mutations and fumarate hydratase inactivation in uterine adenomyomas

STUDY QUESTION: Do the uterine leiomyoma driver events – mediator complex subunit 12 (MED12) mutations, high mobility group AT-hook (HMGA2) overexpression, and fumarate hydratase (FH) inactivation – also contribute to the development of uterine adenomyomas? SUMMARY ANSWER: MED12 mutations and FH def...

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Detalles Bibliográficos
Autores principales: Heikkinen, Tuomas, Äyräväinen, Anna, Hänninen, Janne, Ahvenainen, Terhi, Bützow, Ralf, Pasanen, Annukka, Vahteristo, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276694/
https://www.ncbi.nlm.nih.gov/pubmed/30895261
http://dx.doi.org/10.1093/hropen/hoy020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276694/
https://www.ncbi.nlm.nih.gov/pubmed/30895261
http://dx.doi.org/10.1093/hropen/hoy020

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