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A single seizure selectively impairs hippocampal‐dependent memory and is associated with alterations in PI3K/Akt/mTOR and FMRP signaling

OBJECTIVE: A single brief seizure before learning leads to spatial and contextual memory impairment in rodents without chronic epilepsy. These results suggest that memory can be impacted by seizure activity in the absence of epilepsy pathology. In this study, we investigated the types of memory affe...

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Detalles Bibliográficos
Autores principales:	Holley, Andrew J., Hodges, Samantha L., Nolan, Suzanne O., Binder, Matthew, Okoh, James T., Ackerman, Kaylin, Tomac, Lindsey A., Lugo, Joaquin N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Full‐length Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276778/ https://www.ncbi.nlm.nih.gov/pubmed/30525120 http://dx.doi.org/10.1002/epi4.12273

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