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Wobble uridine tRNA modification: a new vulnerability of refractory melanoma
The enzymes catalysing the modification of the wobble uridine (U(34)) of tRNAs (U(34)-enzymes) play an important role in tumor development. We have recently demonstrated that the U(34)-enzymes are crucial in the survival of glycolytic melanoma cultures through a codon-specific regulation of HIF1α mR...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276846/ https://www.ncbi.nlm.nih.gov/pubmed/30525092 http://dx.doi.org/10.1080/23723556.2018.1513725 |