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On your marks, get SET(D1A): the race to protect stalled replication forks

We recently identified that methylation of lysine 4 of histone H3 (H3K4) by SETD1A (SET domain containing 1A) maintains genome stability by protecting newly-replicated DNA from degradation. Mechanistically, SETD1A-dependent histone methylation regulates nucleosome mobilisation by FANCD2 (FA compleme...

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Detalles Bibliográficos
Autores principales:	Begum, Shabana, Goula, Amalia, Bayley, Rachel, Higgs, Martin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Author’s Views
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276854/ https://www.ncbi.nlm.nih.gov/pubmed/30525090 http://dx.doi.org/10.1080/23723556.2018.1511209

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