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Identification of differentially methylated cell-types in Epigenome-Wide Association Studies
An outstanding challenge of Epigenome-Wide Association Studies (EWAS) performed in complex tissues is the identification of the specific cell-type(s) responsible for the observed differential DNA methylation. Here, we present a novel statistical algorithm, called CellDMC, which is able to identify n...
Autores principales: | Zheng, Shijie C, Breeze, Charles E., Beck, Stephan, Teschendorff, Andrew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277016/ https://www.ncbi.nlm.nih.gov/pubmed/30504870 http://dx.doi.org/10.1038/s41592-018-0213-x |
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