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G-quadruplexes formation in the 5’UTRs of mRNAs associated with colorectal cancer pathways
RNA G-quadruplexes (rG4) are stable non-canonical secondary structures composed of G-rich sequences. Many rG4 structures located in the 5’UTRs of mRNAs act as translation repressors due to their high stability which is thought to impede ribosomal scanning. That said, it is not known if these are mRN...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277105/ https://www.ncbi.nlm.nih.gov/pubmed/30507959 http://dx.doi.org/10.1371/journal.pone.0208363 |