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RNA virus evasion of nonsense-mediated decay

Nonsense-mediated decay (NMD) is a host RNA control pathway that removes aberrant transcripts with long 3’ untranslated regions (UTRs) due to premature termination codons (PTCs) that arise through mutation or defective splicing. To maximize coding potential, RNA viruses often contain internally loca...

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Detalles Bibliográficos
Autores principales: May, Jared P., Yuan, Xuefeng, Sawicki, Erika, Simon, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277124/
https://www.ncbi.nlm.nih.gov/pubmed/30452463
http://dx.doi.org/10.1371/journal.ppat.1007459