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Spen limits intestinal stem cell self-renewal
Precise regulation of stem cell self-renewal and differentiation properties is essential for tissue homeostasis. Using the adult Drosophila intestine to study molecular mechanisms controlling stem cell properties, we identify the gene split-ends (spen) in a genetic screen as a novel regulator of int...
Autores principales: | Andriatsilavo, Maheva, Stefanutti, Marine, Siudeja, Katarzyna, Perdigoto, Carolina N., Boumard, Benjamin, Gervais, Louis, Gillet-Markowska, Alexandre, Al Zouabi, Lara, Schweisguth, François, Bardin, Allison J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277126/ https://www.ncbi.nlm.nih.gov/pubmed/30452449 http://dx.doi.org/10.1371/journal.pgen.1007773 |
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